The SLE-CVD Calculator

Systemic lupus erythematosus (SLE) significantly increases the risk of cardiovascular disease (CVD), yet traditional risk calculators often fail to account for SLE-specific factors like disease severity and unique biomarkers. To address this gap, we developed SLECRISK, a personalized tool that integrates SLE-related variables such as disease duration, specific autoantibodies, and organ involvement with traditional CVD risk factors. Compared to standard models, SLECRISK is more sensitive, identifying over three times as many high-risk patients, particularly young women with severe SLE who might otherwise be overlooked.